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If you are interested in Korean medical aesthetics, you have likely heard of the "Salmon Injection." But when you look closer at the ingredients, you often see two confusing acronyms: PDRN and PN. Are they the same thing? Not exactly. While they originate from the same source, their medical applications and cosmetic effects are distinct. Here is a comprehensive breakdown of these two powerful regenerative ingredients to help you choose the right product for your customers.     1. The Common Origin: Salmon DNA Both PDRN and PN are DNA fragments derived from the sperm of Salmon (Oncorhynchus keta) or Trout. Why Salmon? Salmon DNA base composition is highly similar to human DNA (approximately 95% match). This ensures high biocompatibility, meaning there is very little risk of immune rejection or side effects when injected into the human body.     2. PDRN (Polydeoxyribonucleotide): The Rapid Healer Think of PDRN as "Medicine for Wounds.” Structure: PDRN consists of shorter DNA chains with a lower molecular weight. Mechanism: It works on the adenosine A2A receptors in the body to trigger a rapid anti-inflammatory response and promote angiogenesis (the formation of new blood vessels). Key Benefits: Tissue Repair: Accelerates the healing of wounds, ulcers, and scars. Anti-Inflammation: Reduces redness and swelling significantly. Scalp Care: Often used in mesotherapy for hair loss to improve blood circulation in the scalp. Texture: It is a liquid solution (water-like viscosity), making it easy to absorb but less suitable for building structure in the skin.     3. PN (Polynucleotide): The Skin Architect Think of PN as "Construction Material for the Skin.” Structure: PN is a longer, more complex DNA chain with a higher molecular weight than PDRN. It is essentially a more concentrated and viscous form of PDRN. Mechanism: Because it is heavier and more viscous, PN doesn't just heal; it acts as a 3D scaffold within the dermis. It physically supports the skin structure while slowly breaking down to fuel skin regeneration. Key Benefits: ECM Restoration: It regenerates the Extracellular Matrix (ECM), increasing skin thickness and density. Elasticity & Hydration: It restores the oil-water balance and improves skin elasticity (famous for the Rejuran Healer effect). Long-lasting: Due to its larger size, it stays in the skin longer than PDRN, providing sustained regenerative effects.      4. Key Differences at a Glance Feature PDRN PN Full Name Polydeoxyribonucleotide Polynucleotide Molecular Weight Low (Short DNA chains) High (Long DNA chains) Viscosity Low (Liquid) High (Gel-like) Primary Goal Healing & Anti-inflammation Regeneration & Support Main Use Wound healing, Hair mesotherapy Anti-aging, Skin barrier repair, Fine lines     The choice between PDRN and PN depends on the goal. If the objective is to quickly heal damaged tissue, treat inflammation, or improve scalp health, PDRN is the effective choice. However, if the goal is aesthetic anti-aging—improving skin elasticity, reducing fine lines, and thickening a thin skin barrier—PN is the superior option. In the current 2025 market, PN (found in products like Rejuran) is the dominant standard for "Skin Boosters," while PDRN retains its value in therapeutic and mesotherapy sectors.

Why Authenticity Matters in Korean Aesthetics K-Beauty has taken the world by storm, and Korean dermal fillers are at the forefront of this trend. Brands like Neuramis, Revolax, and Bonetta are loved globally for their high quality and competitive pricing. However, as popularity grows, so does the market for counterfeit products. Using fake fillers is not just a waste of money—it is a serious health risk. Counterfeits often contain industrial-grade silicone or non-sterile substances that can cause infection, necrosis, and permanent scarring. As a certified supplier of authentic Korean medical aesthetics, we believe safety comes first. Here is your ultimate guide to identifying genuine products.     1. Check the Security Seals and Holograms Most premium Korean filler brands utilize advanced anti-counterfeiting technology. The first thing you should inspect is the box. Holographic Stickers: Authentic products usually seal their boxes with a tamper-evident holographic sticker. If the sticker is missing, broken, or looks like a simple printed image without a shine, it is a red flag. QR Codes: Many manufacturers now include a QR code on the side or back of the package. When scanned with your smartphone, it should lead you to the official manufacturer's verification page. Tip: If the QR code leads to a generic website or a dead link, do not use the product.     2. Inspect the Lot Number and Expiration Date Legitimate manufacturers strictly control their inventory. Every box of fillers comes with a specific Lot Number and Expiration Date. Match the Syringe: Open the box (if you have already purchased it) and check the syringe or blister pack. The Lot Number on the syringe must match the Lot Number printed on the box. Print Quality: On fake products, these numbers are often stamped poorly, smudged, or printed in a font that looks different from the rest of the packaging.     3. Examine the Packaging and Typography Counterfeiters often make mistakes in the details. Look closely at the printing quality. Typos: Check for spelling errors in English or awkward phrasing. Korean Characters: If you are familiar with Korean, check the Hangul (Korean text). Fakes made in other countries often use broken or incorrect Korean characters. Color Fading: Authentic packaging has sharp, vibrant colors. Fakes often look washed out or slightly pixelated.     4. The Price Trap: "Too Good to Be True” We understand that as a clinic owner or distributor, you want the best wholesale price. However, there is a limit to how cheap a genuine product can be. If a seller offers a "Wholesale Price" that is significantly lower (e.g., 50% cheaper) than the average market rate, be extremely cautious. These are often: Counterfeit goods. Expired or near-expiry products. Products stored improperly (exposed to high heat during shipping). Authentic wholesalers maintain a competitive but realistic price range because we source directly from manufacturers and adhere to strict storage protocols.     5. Buy from a Certified Korean Wholesaler The safest way to avoid fakes is to choose your supplier carefully. Do not buy from anonymous sellers on social media who cannot provide business verification. Why choose us? 100% Authentic Guarantee: We source directly from official Korean manufacturers. Cold Chain System: We ensure that temperature-sensitive products (like toxins) are shipped with proper insulation and ice packs. Verified Seller: We are a registered business in Korea specializing in global B2B export.     Your clients trust you with their faces. Don't compromise that trust with dubious products. Always verify your fillers before use. Looking for a reliable source of authentic Korean dermal fillers and toxins? Check out our [👉Best Selling Collection Here] and enjoy safe, global shipping.  

You’ve invested in your beauty with a Botox or filler treatment. Now, the results depend on how well you care for your skin during the recovery phase. While these procedures are non-surgical, proper aftercare is critical to preventing side effects like migration, bruising, or infection, and to ensuring the longevity of your results. Here is a strictly medically-based guide on what to do—and what to avoid—immediately after your procedure.   1. The "Golden Time" Rules (First 4 Hours) The first few hours are crucial for the product to settle correctly. Stay Upright (Botox Only): Do not lie down or bend over for at least 4 hours after Botox injections. Lying flat can cause the toxin to migrate to unintended muscles, potentially leading to drooping eyelids (ptosis). No Touching: Do not rub, massage, or apply pressure to the treated area. For fillers, pressure can deform the shape of the injected gel before it sets.     2. Critical Restrictions (First 24-48 Hours) To minimize inflammation and bruising, strictly avoid the following for at least 24 to 48 hours: No Strenuous Exercise: Heavy lifting, cardio, or any activity that increases your heart rate can increase blood flow to the face, leading to significant swelling and bruising. Avoid Heat: Stay away from saunas, hot tubs, steam rooms, and hot showers. Heat dilates blood vessels, which worsens swelling and can affect the product's settlement. No Alcohol: Alcohol acts as a blood thinner. Consuming it immediately after treatment increases the risk of bleeding and bruising at the injection sites.     3. Skincare & Makeup Guidelines Makeup: Avoid applying makeup for at least 12 to 24 hours. The injection sites are tiny puncture wounds; covering them with makeup brushes or sponges can introduce bacteria and cause infection. Active Ingredients: Paus using strong active ingredients such as Retinol, Vitamin C, or AHAs/BHAs for 3–5 days. Your skin may be sensitive, and these ingredients can cause irritation. Stick to a gentle, hydrating cleanser and moisturizer.     4. Managing Pain & Swelling Cold Compress: Apply an ice pack wrapped in a clean cloth for 10–15 minutes an hour to reduce swelling. Note: Do not apply ice directly to the skin. Pain Relief: If you feel discomfort, take Acetaminophen (e.g., Tylenol). Avoid NSAIDs like Ibuprofen or Aspirin, as they thin the blood and can worsen bruising.     5. When to Seek Medical Help While mild redness, swelling, and bruising are normal, be aware of these warning signs: Vascular Occlusion (Fillers): If you notice a specific area turning white (blanching), becoming extremely painful, or developing a blotchy pattern, seek immediate medical attention. This could indicate a blocked blood vessel. Signs of Infection: Increasing warmth, fever, or pus at the injection site requires professional care.